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Article

Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density.

The Journal of clinical investigation - 1 Jun 2014

Mesner Larry D, Ray Brianne, Hsu Yi-Hsiang, Manichaikul Ani, Lum Eric, Bryda Elizabeth C, Rich Stephen S, Rosen Clifford J, Criqui Michael H, Allison Matthew, Budoff Matthew J, Clemens Thomas L, Farber Charles R

Abstract excerpt

Patient bone mineral density (BMD) predicts the likelihood of osteoporotic fracture. While substantial progress has been made toward elucidating the genetic determinants of BMD, our understanding of the factors involved remains incomplete. Here, using a systems genetics approach in the mouse, we...

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Topics

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Share to Bone Density
Share to Carrier Proteins
Share to Gene Knockdown Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

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Source

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Identifiers

PMID: 24789909
DOI: 10.1172/JCI73072
PMCID: PMC4038574

Genes

BICC1
PKD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24789909-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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