Article
Enhanced Identification of Potential Pleiotropic Genetic Variants for Bone Mineral Density and Breast Cancer.
Calcified tissue international - 1 Nov 2017
Peng Cheng, Lou Hui-Ling, Liu Feng, Shen Jie, Lin Xu, Zeng Chun-Ping, Long Ji-Rong, Su Kuan-Jui, Zhang Lan, Greenbaum Jonathan, Deng Wei-Feng, Li Yu-Mei, Deng Hong-Wen
Abstract excerpt
Epidemiological and clinical evidences have shown that bone mineral density (BMD) has a close relationship with breast cancer (BC). They might potentially have a shared genetic basis. By incorporating information about these pleiotropic effects, we may be able to explore more of the traits' total heritability. We applied a recently developed conditional false discovery rate (cFDR) method to the summary statistics...
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