Article

Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice

2020-09-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Triggering receptor expressed on myeloid cells 2 (TREM2) is expressed in the brain exclusively on microglia and genetic variants are linked to neurodegenerative diseases including Alzheimer’s disease (AD), frontotemporal dementia (FTD) and Nasu Hakola Disease (NHD). The <italic>Trem2</italic> variant R47H, confers substantially elevated risk of developing late o...

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Literature Corpus work: b7245d8e-461b-5047-ac6a-532c8c410967
DOI: 10.21203/rs.3.rs-33900/v2

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