Article

Computational insight in the identification of nonsynonymous single nucleotide polymorphism affecting the structure and function of Interleukin-4

2024-08-25

Abstract excerpt

Abstract Background IL4 is a versatile cytokine essentially known for differentiation, proliferation, and cell death in cells. Its dysregulation has been found to be associated with the development of inflammatory disorders. Objective The goal of the current investigation is to identify and select non-synonymous single nucleotide polymorphisms (nsSNPs) in the IL-4 gene by employing computational methods which may...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b5c3568d-a47c-5348-b2de-5e3c3268d716
DOI: 10.22541/au.172457644.44902764/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Computational insight in the identification of nonsynonymous single nucleotide polymorphism affecting the structure and function of Interleukin-4DOI 10.22541/au.172457644.44902764/v1Read

Computational Insight in the Identification of Non-Synonymous Single-Nucleotide Polymorphism Affecting the Structure and Function of Interleukin-4.Semantic proximity Read

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene.Semantic proximity Read

Prediction of the most deleterious non-synonymous SNPs in the human IL1B gene: evidence from bioinformatics analyses.Semantic proximity Read

In-silico analysis unravels the structural and functional consequences of non-synonymous SNPs in the human IL-10 geneSemantic proximity Read

Insilico prediction and functional analysis of nonsynonymous SNPs in human CTLA4 gene.Semantic proximity Read

The pathogenic effect of SNPs on structure and function of human TLR4 using a computational approach.Semantic proximity Read

A comprehensive in Silico analysis of the functional and structural impact of single nucleotide polymorphisms (SNPs) in the human IL-33 gene.Semantic proximity Read

Demystifying the implications of disease-susceptible missense SNPs within CTLA-4 ligand binding domain and its interaction towards B7-1 protein complex: Bioinformatics-driven evidence.Semantic proximity Read

Identification of Most Lethal Non-synonymous SNPs in Tollip gene- An In-Silico AnalysisSemantic proximity Read

In silico analysis of missense SNPs in TNFR1a and their possible therapeutic or pathogenic role in immune diseases.Semantic proximity Read

Comprehensive characterization of high-risk coding and non-coding single nucleotide polymorphisms of human CXCR4 gene.Semantic proximity Read

Deleterious effects of non-synonymous single nucleotide variants of human IL-1β gene.Semantic proximity Read