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A comprehensive in Silico analysis of the functional and structural impact of single nucleotide polymorphisms (SNPs) in the human IL-33 gene.

Computational biology and chemistry - 1 Oct 2021

Falahi Sara, Karaji Ali Gorgin, Koohyanizadeh Farzaneh, Rezaiemanesh Alireza, Salari Farhad

Abstract excerpt

Interleukin 33 (IL-33) is the latest member of the IL-1 cytokine family, which plays both pro - and anti-inflammatory functions. Numerous Single-nucleotide polymorphisms (SNPs) in the IL-33 gene have been recognized to be associated with a vast variety of inflammatory disorders. SNPs associated studies have become a crucial approach in uncovering the genetic background of human diseases. However, distinguishing...

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PMID: 34455166
DOI: 10.1016/j.compbiolchem.2021.107560

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