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Article

Comprehensive characterization of high-risk coding and non-coding single nucleotide polymorphisms of human CXCR4 gene.

PloS one - 1 Jan 2024

Sarkar Bonoshree, Mondal Muhammad Safiul Alam, Rahman Taibur, Hosen Md Ismail, Rahman Atiqur

Abstract excerpt

CXCR4, a chemokine receptor known as Fusin or CD184, spans the outer membrane of various human cells, including leukocytes. This receptor is essential for HIV infection as well as for many vital cellular processes and is implicated to be associated with multiple pathologies, including cancers. This study employs various computational tools to investigate the molecular effects of disease-vulnerable germ-line...

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Share to CXCR4 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Docking Simulation

Share to Polymorphism, Single Nucleotide

Share to Protein Stability

Share to Receptors, CXCR4

Source

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Identifiers

PMID: 39715225
DOI: 10.1371/journal.pone.0312733
PMCID: PMC11665994

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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