Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computational Insight in the Identification of Non-Synonymous Single-Nucleotide Polymorphism Affecting the Structure and Function of Interleukin-4.

Proteomics. Clinical applications - 1 Mar 2025

Roy Pratima, Sharma Siddharth, Baranwal Manoj

Abstract excerpt

BACKGROUND: IL4 is a versatile cytokine essentially known for differentiation, proliferation and cell death in cells. Its dysregulation has been found to be associated with the development of inflammatory disorders. OBJECTIVE: The goal of the current investigation is to identify and select non-synonymous single-nucleotide polymorphisms (nsSNPs) in the IL-4 gene by employing computational methods which may have a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Interleukin-4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 39648289
DOI: 10.1002/prca.202400070

Genes

IL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computational Insight in the Identification of Non-Synonymous Single-Nucleotide Polymorphism Affecting the Structure and Function of Interleukin-4.PMID 39648289Read ↗

Computational insight in the identification of nonsynonymous single nucleotide polymorphism affecting the structure and function of Interleukin-4Semantic proximity Read ↗

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene.Semantic proximity Read ↗

Prediction of the most deleterious non-synonymous SNPs in the human IL1B gene: evidence from bioinformatics analyses.Semantic proximity Read ↗

In-silico analysis unravels the structural and functional consequences of non-synonymous SNPs in the human IL-10 geneSemantic proximity Read ↗

Insilico prediction and functional analysis of nonsynonymous SNPs in human CTLA4 gene.Semantic proximity Read ↗

The pathogenic effect of SNPs on structure and function of human TLR4 using a computational approach.Semantic proximity Read ↗

A comprehensive in Silico analysis of the functional and structural impact of single nucleotide polymorphisms (SNPs) in the human IL-33 gene.Semantic proximity Read ↗

Identification of Most Lethal Non-synonymous SNPs in Tollip gene- An In-Silico AnalysisSemantic proximity Read ↗

Demystifying the implications of disease-susceptible missense SNPs within CTLA-4 ligand binding domain and its interaction towards B7-1 protein complex: Bioinformatics-driven evidence.Semantic proximity Read ↗

Computational analysis of structural and functional evaluation of the deleterious missense variants in the human CTLA4 gene.Semantic proximity Read ↗

The Interleukin-1 (IL-1) Superfamily Cytokines and Their Single Nucleotide Polymorphisms (SNPs).Semantic proximity Read ↗

In silico analysis of missense SNPs in TNFR1a and their possible therapeutic or pathogenic role in immune diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.