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Article

Deleterious effects of non-synonymous single nucleotide variants of human IL-1β gene.

Chemical biology & drug design - 1 Oct 2017

Zhang Yue-Hui, Song Jia, Zhang Jing, Shao Jiang

Abstract excerpt

The IL-1β gene is currently topic of interest for its important role in the pathogenesis of intervertebral disk degeneration. The new sequencing technology makes it crucial to study the effects of variants in IL-1β. Thus, 714 IL-1β variants with evidence supporting were collected from the EMBL database. Among them, 62 were non-synonymous single nucleotide variants (nsSNVs). Furthermore, six common nsSNVs were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28296211
DOI: 10.1111/cbdd.12976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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