Article

Liver-specific polygenic risk score is more strongly associated than genome-wide score with Alzheimer’s disease diagnosis in a case-control analysis

2021-05-02

Abstract excerpt

Although our understanding of Alzheimer’s disease (AD) has greatly improved in recent years, the root cause remains unclear, making it difficult to find effective diagnosis and treatment options. Our understanding of the pathophysiology underlying AD has benefited from genomic analyses, including those that leverage polygenic risk score (PRS) models of disease. In many aspects of genomic research the use of functi...

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Literature Corpus work: b56f0eae-b061-5adf-8cca-dc0c4670b651
DOI: 10.1101/2021.04.29.21256279

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