Article

The genetic architecture of dementia risk: how Alzheimer’s disease vulnerability converges on lipid metabolism and immune cell networks

2026-06-16

Abstract excerpt

Although genome-wide association studies (GWAS) have identified numerous dementia risk loci, their cell-type and tissue-specific contexts remain largely unresolved. We introduced HPA GeneSet Explorer, a statistical pipeline designed to systemically map Genome wide association study (GWAS) disease risk genes across the Human Protein Atlas (HPA). This approach generates a multiscale transcriptomic map of genetic ris...

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Literature Corpus work: 3f1486ae-fb1d-5b22-bb25-35c5a69664a9
DOI: 10.64898/2026.06.11.731645

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