Article

Integrative multi-omics approaches identify molecular pathways and improve Alzheimer’s Disease risk prediction

2025-06-02

Abstract excerpt

Alzheimer’s Disease (AD) is the most prevalent condition that impacts the aging population, with no effective treatment or singular underlying causal factor identified. As a complex disease, characterizing the genetic risk of developing AD has proven to be difficult; polygenic scores (PGS) exclusively use common variants which fail to fully capture disease heterogeneity. This study used univariate and multivariate...

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Literature Corpus work: 7e2e9ef4-8025-5a39-a06d-9a700d8b3543
DOI: 10.1101/2025.05.31.25328688

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