Article

Analysis of Alzheimer’s disease Polygenic Risk Scores using RNA-sequencing provides further novel biological pathways

2022-06-29

Abstract excerpt

Polygenic risk scores (PRS) have been widely adopted as a tool for measuring common variant liability and it has been shown to predict lifetime risk of Alzheimer’s disease (AD) development. However, the relationship between PRS and AD pathogenesis is largely unknown. We aimed to address some of the knowledge gaps with respect to the downstream molecular consequences associated with PRS. We also make a direct compa...

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Literature Corpus work: d702bd57-9dfd-56ac-9c5b-e02171731ea0
DOI: 10.1101/2022.06.29.22276952

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