Article

Micropillar-induced changes in cell nucleus morphology enhance bone regeneration by modulating the secretome

2025-01-07

Abstract excerpt

<title>Abstract</title> <p>Nuclear morphology, which modulates chromatin architecture, plays a critical role in regulating gene expression and cell functions. While most research has focused on the direct effects of nuclear morphology on cell fate, its impact on the cell secretome and surrounding cells remains largely unexplored, yet is especially crucial for cell-based therapies. In this study, we fabricated imp...

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Literature Corpus work: b55579a8-65b7-5d5f-b2a7-fca46aa766ee
DOI: 10.21203/rs.3.rs-5530535/v1

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