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Article

Mechanical Phenotyping of MG63s Following Vibrational Stimulation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 15 May 2026

Pereira Sousa Rui Pedro, Reid Stuart, Dalby Matthew J, Jimenez Melanie, Childs Peter G

Abstract excerpt

Nanovibration, a kilohertz-frequency, nano-amplitude mechanical stimulation, has been shown to drive osteogenesis; however, the mechanisms remain unclear. Mechanotransduction has been proposed with limited cell population-level evidence. We propose the use of a high-throughput mechanical phenotyping technique, Real-Time Deformability Cytometry (RT-DC), to observe mechanical changes in an osteogenic model, MG63s....

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Identifiers

PMID: 42068221
DOI: 10.1096/fj.202504885R
PMCID: PMC13135235

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