Article

Matrix compliance regulates cellular and nuclear confinement of fibroblasts in tunable protein-based hydrogel microenvironments

2025-07-14

Abstract excerpt

The extracellular matrix (ECM) influences cellular behavior, fate, and various mechanisms underlying homeostasis, development, and disease. Biophysical and biochemical properties of the ECM are known to affect three-dimensional (3D) cellular behavior, and phenotype that regulate a wide range of pathological conditions. Tunable biomimetic hydrogels are extensively employed to regulate cellular dynamics in defined 3...

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Literature Corpus work: aff1e158-6eaf-53df-b6e7-d0b3ed62f74d
DOI: 10.1101/2025.07.09.663931

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