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Article

Multi-Tissue Neocortical Transcriptome-Wide Association Study Implicates 8 Genes Across 6 Genomic Loci in Alzheimer’s Disease

2020-06-30

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease (AD), an incurable neurodegenerative disease, currently affecting 1.75% of the United States population, with projected growth to 3.46% by 2050. Identifying common genetic variants driving differences in transcript expression that confer AD-risk is necessary to elucidate AD mechanism and develop therapeutic interventions. We modify the FUSION Transcriptome Wide Association...

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Literature Corpus work
b51ac2df-11ab-5767-bf79-5fe3304ff202
DOI
10.1101/2020.06.29.178590
Open publication

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Multi-Tissue Neocortical Transcriptome-Wide Association Study Implicates 8 Genes Across 6 Genomic Loci in Alzheimer’s DiseaseDOI 10.1101/2020.06.29.178590
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