Article

Identification of novel associations of candidate loci with Alzheimer’s disease by leveraging the shared genetic basis with hippocampal volume

2024-10-02

Abstract excerpt

<h4>Objective</h4> Alzheimer’s disease (AD) is a complex neurodegenerative disorder with a considerable genetic contribution that remains not fully understood. The hippocampus plays a critical role in learning and memory, with its volume loss being a core hallmark of AD. Hippocampal volume also has a strong heritable component and its genetic underpinnings may help us to understand the complex biological mechanism...

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Literature Corpus work: b616c821-1269-58b2-a7ea-9040ec0f1db9
DOI: 10.1101/2024.10.01.24314738

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