Article

Parallel functional testing identifies enhancers active in early postnatal mouse brain

2021-01-15

Abstract excerpt

<h4>ABSTRACT</h4> Enhancers are cis-regulatory elements that play critical regulatory roles in modulating developmental transcription programs and driving cell-type specific and context-dependent gene expression in the brain. The development of massively parallel reporter assays (MPRAs) has enabled high-throughput functional screening of candidate DNA sequences for enhancer activity. Tissue-specific screening of...

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Literature Corpus work: b3807c9c-e202-5dfb-94e3-e8307c75365b
DOI: 10.1101/2021.01.15.426772

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