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Article

VISTA Enhancer browser: an updated database of tissue-specific developmental enhancers.

Nucleic acids research - 6 Jan 2025

Kosicki Michael, Baltoumas Fotis A, Kelman Guy, Boverhof Joshua, Ong Yeongshnn, Cook Laura E, Dickel Diane E, Pavlopoulos Georgios A, Pennacchio Len A, Visel Axel

Abstract excerpt

Regulatory elements (enhancers) are major drivers of gene expression in mammals and harbor many genetic variants associated with human diseases. Here, we present an updated VISTA Enhancer Browser (https://enhancer.lbl.gov), a database of transgenic enhancer assays conducted in developing mouse embryos in vivo. Since the original publication in 2007, the database grew nearly 20-fold from 250 to over 4500...

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Share to Databases, Genetic
Share to Databases, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Embryonic Development

Share to Enhancer Elements, Genetic

Share to Gene Expression Regulation, Developmental

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Source

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Identifiers

PMID: 39470740
DOI: 10.1093/nar/gkae940
PMCID: PMC11701537

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