Article

An <i>in vivo</i> massively parallel platform for deciphering tissue-specific regulatory function

2022-11-25

Abstract excerpt

Genetic studies are rapidly identifying non-protein-coding human disease-associated loci. Understanding the regulatory mechanisms underlying these loci remains a challenge because the causal variants and the tissues in which they act are often unclear. Massively parallel reporter assays (MPRAs) have the potential to link differences in genome sequence, including genetic variants, to tissue-specific regulatory func...

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Literature Corpus work: e170c056-abca-58e6-aa7f-434251446af9
DOI: 10.1101/2022.11.23.517755

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