Article

Uncovering Hidden Enhancers Through Unbiased <i>In Vivo</i> Testing

2022-05-30

Abstract excerpt

Transcriptional enhancers are a predominant class of noncoding regulatory elements that activate cell type-specific gene expression. Tissue-specific enhancer-associated chromatin signatures have proven useful to identify candidate enhancer elements at a genome-wide scale, but their sensitivity for the comprehensive detection of all enhancers active in a given tissue in vivo remains unclear. Here we show that a su...

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Literature Corpus work: 577b2122-91d2-51d4-b659-f3ce038cf1a3
DOI: 10.1101/2022.05.29.493901

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