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Article

Functional anatomy of distant-acting mammalian enhancers.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 1 Jan 2013

Dickel D E, Visel A, Pennacchio L A

Abstract excerpt

Transcriptional enhancers are a major class of functional element embedded in the vast non-coding portion of the human genome. Acting over large genomic distances, enhancers play critical roles in the tissue and cell type-specific regulation of genes, and there is mounting evidence that they contribute to the aetiology of many human diseases. Methods for genome-wide mapping of enhancer regions are now available,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23650633
DOI: 10.1098/rstb.2012.0359
PMCID: PMC3682724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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