Article
Bridging between mouse and human enhancer-promoter long-range interactions in neural stem cells, to understand enhancer function in neurodevelopmental disease
2022-05-26
Abstract excerpt
Non-coding variation in complex human disease has been well established by genome-wide association studies, and it is thought to involve regulatory elements, such as enhancers, whose variation affects the expression of the gene responsible for the disease. The regulatory elements often lie far from the gene they regulate, or within introns of genes differing from the regulated gene, making it difficult to identify...
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Identifiers and source
- Literature Corpus work
- 956b83d4-3226-5cca-a337-fd35769c4cc7
- DOI
- 10.1101/2022.05.26.493430