Learning about mammalian gene regulation from functional enhancer assays in the mouse.

Abstract excerpt

Enhancer biology is emerging as a critical area of research that informs studies of evolution, development, and disease. From early experiments that defined and mapped the first enhancers to recent enhancer models of human disease, functional experiments in the mouse have played a central role in revealing enhancer biology. Three decades of in vivo enhancer studies in mouse have laid the groundwork for the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Enhancer Elements, Genetic
• Share to Evolution, Molecular
• Share to Gene Expression Regulation, Developmental