Article

Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance

2021-04-05

Abstract excerpt

<h4>Background</h4> Non-coding regulatory elements (NCREs), such as enhancers, play a crucial role in gene regulation and genetic aberrations in NCREs can lead to human disease, including brain disorders. The human brain is complex and can be affected by numerous disorders; many of these are caused by genetic changes, but a multitude remain currently unexplained. Understanding NCREs acting during brain developmen...

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Literature Corpus work: 9c3526a5-c389-59d1-aec8-05771c16f707
DOI: 10.1101/2021.04.05.438382

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