Article

<i>C. elegans</i> establishes germline versus soma by balancing inherited histone methylation

2020-01-23

Abstract excerpt

<h4>ABSTRACT</h4> Embryos undergo extensive reprogramming at fertilization to prevent the inappropriate inheritance of histone methylation. In C. elegans, this reprogramming is mediated by the H3K4me2 demethylase, SPR-5, and the H3K9 methyltransferase, MET-2. In contrast to this reprogramming, the H3K36 methyltransferase, MES-4, maintains H3K36me2/3 at germline genes between generations to help re-establish the...

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Literature Corpus work: af0caee2-d805-50b3-a018-8a3ebbaa96ae
DOI: 10.1101/2020.01.22.914580

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