Article

Maternal histone methyltransferases antagonistically regulate monoallelic expression in <i>C. elegans</i>

2024-01-25

Abstract excerpt

Undefined epigenetic programs act to probabilistically silence individual autosomal alleles, generating unique individuals, even from genetic clones. This sort of random monoallelic expression can explain variation in traits and diseases that differences in genes and environments cannot. Here, we developed the nematode Caenorhabditis elegans to study monoallelic expression in whole tissues, and defined a developm...

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Literature Corpus work: 26446bc2-6c0f-5819-85cc-e8053031dde9
DOI: 10.1101/2024.01.22.576748

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