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Article

Epigenetic dynamics during germline development: insights from Drosophila and C. elegans

20 Dec 2022

Abstract excerpt

Gametogenesis produces the only cell type within a metazoan that contributes both genetic and epigenetic information to the offspring. Extensive epigenetic dynamics are required to express or repress gene expression in a precise spatiotemporal manner. On the other hand, early embryos must be extensively reprogrammed as they begin a new life cycle, involving intergenerational epigenetic inheritance. Seminal work...

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PMID: 36549194
DOI: 10.1016/j.gde.2022.102017

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