Article

The Dream and MEC NuRD Complexes reinforce SPR-5/MET-2 maternal reprogramming to maintain the germline-soma distinction

2025-07-27

Abstract excerpt

<h4>ABSTRACT</h4> The proper coordination of transcription factors, ATP dependent chromatin remodelers and histone modifications is essential for tissue specific gene expression, but how gene expression is regulated at these different levels is not well understood. In C. elegans , H3K4 methylation that is acquired in the germline is reprorgammed at fertilization by the H3K4me1/2 demethlyase SPR-5/LSD1/KDM1A and...

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Literature Corpus work: 98f5134e-3899-5075-a549-f7dcf60bed56
DOI: 10.1101/2025.07.23.666413

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