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Maternal H3K36 and H3K27 HMTs protect germline immortality via regulation of the transcription factor LIN-15B

2022-03-18

Abstract excerpt

<h4>ABSTRACT</h4> Maternally synthesized products play critical roles in development of offspring. A premier example is the C. elegans H3K36 methyltransferase MES-4, which is essential for germline survival and development in offspring. How maternal MES-4 protects germline immortality is not well understood, but its role in H3K36 methylation hinted that it may regulate gene expression in Primordial Germ Cells (P...

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Literature Corpus work
704d475c-48af-57c6-a965-74ab71050c2c
DOI
10.1101/2022.03.17.484692
Open publication

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