Article

<i>Caenorhabditis elegans</i> MES-3 is a highly divergent ortholog of the canonical PRC2 component SUZ12

2022-04-09

Abstract excerpt

<h4>SUMMARY</h4> Polycomb Repressive Complex 2 (PRC2) catalyzes the mono-, di, and trimethylation of histone protein H3 on lysine 27 (H3K27), which is strongly associated with transcriptionally silent chromatin. The functional core of PRC2 is highly conserved in animals and consists of four subunits. One of these, SUZ12, has not been identified in the genetic model Caenorhabditis elegans , whereas C. elegans PR...

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Literature Corpus work: adbb9d4d-eb73-566b-840f-9d48afc1b622
DOI: 10.1101/2022.04.07.487461

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