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Article

MIG-32 and SPAT-3A are PRC1 homologs that control neuronal migration in Caenorhabditis elegans.

Development (Cambridge, England) - 1 Mar 2009

Karakuzu Ozgur, Wang David P, Cameron Scott

Abstract excerpt

The Polycomb repression complex 2 (PRC2) methylates histone H3 lysine 27 at target genes to modify gene expression, and this mark is recognized by PRC1, which ubiquitylates histone H2A. In Caenorhabditis elegans, a complex of the MES-2, MES-3 and MES-6 proteins is functionally analogous to the PRC2 complex, but the functional analog of PRC1, and indeed whether C. elegans has such a complex, has been unclear. We...

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Identifiers

PMID: 19211678
DOI: 10.1242/dev.029363
PMCID: PMC2727560

Genes

PRC1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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