Article

Three classes of response elements for human PRC2 and MLL1/2-trithorax complexes

2017-12-11

Abstract excerpt

<h4>Summary</h4> Polycomb group (PcG) and trithorax group (TrxG) proteins are essential for maintaining epigenetic memory in both embryonic stem cells and differentiated cells. To date, how they are localized to hundreds of specific target genes within a vertebrate genome had remained elusive. Here, by focusing on short cis -acting DNA elements of single functions, we discovered, for the first time, to our knowl...

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Literature Corpus work: be083343-7fd1-5801-a403-26b2de06da99
DOI: 10.1101/232686

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