Article

SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in <i>C. elegans</i>

2020-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Piwi-interacting RNAs (piRNAs) play essential roles in silencing repetitive elements to promote fertility in metazoans. Studies in worms, flies, and mammals reveal that piRNAs are expressed in a sex-specific manner. However, the mechanisms underlying this sex-specific regulation are unknown. Here we identify SNPC-1.3, a variant of a conserved subunit of the snRNA activating protein complex, as a...

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Literature Corpus work: ec1e7b6c-d2b0-5b24-9dd3-ca33965187d8
DOI: 10.1101/2020.08.06.240200

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