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Overlapping and non-overlapping roles of the class-I histone deacetylase-1 corepressors, LET-418, SIN-3, and SPR-1 in <i>Caenorhabditis elegans</i> embryonic development

2020-07-21

Abstract excerpt

Histone deacetylases (HDACs) are divided into four classes. Class-I HDAC, HDAC-1 forms three types of complexes, namely the Nucleosome Remodeling Deacetylase complex, the Sin3 complex, and the CoREST complex, with specific corepressor component Mi2/CHD-3, Sin3, and RCOR1 in human, respectively. The functions of these HDAC-1 complexes are regulated by their corepressors, however, their exact mechanistic roles in se...

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Literature Corpus work
f6e4e107-9f36-561e-a3bd-f7127a350fad
DOI
10.1101/2020.07.21.213561
Open publication

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Overlapping and non-overlapping roles of the class-I histone deacetylase-1 corepressors, LET-418, SIN-3, and SPR-1 in <i>Caenorhabditis elegans</i> embryonic developmentDOI 10.1101/2020.07.21.213561
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