Article

Genetic Insights into the Therapeutic Targets for Essential Hypertension: Mendelian Randomization and Colocalization Analysis

2023-12-27

Abstract excerpt

The prevalence of Essential Hypertension (EH) is increasing globally, and the effectiveness of pharmacological treatments remains far from ideal. Combining Mendelian Randomization (MR) to identify potential drug targets may be key to reducing the disease burden and developing potential treatments. We utilized the UK Biobank cohort (ncase = 54358, ncontrol = 408652) to extract summary statistics for EH and further...

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Literature Corpus work: adbb7930-e348-5a22-8942-11fe9622ec92
DOI: 10.21203/rs.3.rs-3808465/v1

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