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Article

Identification of potential drug targets for erectile dysfunction with single-cell RNA sequencing: A Mendelian randomization study.

Andrology - 1 Mar 2026

Xiang Bo-Yu, Wen Jie, Wang Yun-Hao, Liu Zhen-Rui, An Jin-Shun, Peng Jing-Xuan, Chen Ling-Xiao, Ding Jian, Wang Gui-Lin, Cheng Quan, Li Dong-Jie

Abstract excerpt

BACKGROUND: A subset of patients with erectile dysfunction (ED) responds poorly to current pharmacological treatments, largely due to the limited availability of well-defined therapeutic targets beyond phosphodiesterase 5 inhibitors (PDE5i). METHODS: This study used Mendelian randomization (MR) to identify potential therapeutic targets for ED. Cis-expression quantitative trait loci (cis-eQTL) were sourced from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40518741
DOI: 10.1111/andr.70082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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