Article
Hypertension genetics past, present and future applications.
Journal of internal medicine - 1 Dec 2021
Olczak Kaya J, Taylor-Bateman Victoria, Nicholls Hannah L, Traylor Matthew, Cabrera Claudia P, Munroe Patricia B
Abstract excerpt
Essential hypertension is a complex trait where the underlying aetiology is not completely understood. Left untreated it increases the risk of severe health complications including cardiovascular and renal disease. It is almost 15 years since the first genome-wide association study for hypertension, and after a slow start there are now over 1000 blood pressure (BP) loci explaining ∼6% of the single nucleotide...
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