Article

Dynamic Analysis of Alternative Polyadenylation from Single-Cell RNA-Seq (scDaPars) Reveals Cell Subpopulations Invisible to Gene Expression Analysis

2020-09-24

Abstract excerpt

Alternative polyadenylation (APA) is a major mechanism of post-transcriptional regulation in various cellular processes including cell proliferation and differentiation, but the APA heterogeneity among single cells remains largely unknown. Single-cell RNA sequencing (scRNA-seq) has been extensively used to define cell subpopulations at the transcription level. Yet, most scRNA-seq data have not been analyzed in an...

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Literature Corpus work: ac2353a9-d0a4-587a-96c4-4ce4b6f9312d
DOI: 10.1101/2020.09.23.310649

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