Article

SCPattern: A statistical approach to identify and classify expression changes in single cell RNA-seq experiments with ordered conditions

2016-03-29

Abstract excerpt

<h4>Motivation</h4> With the development of single cell RNA-seq (scRNA-seq) technology, scRNA-seq experiments with ordered conditions (e.g. time-course) are becoming common. Methods developed for analyzing ordered bulk RNA-seq experiments are not applicable to scRNA-seq, since their distributional assumptions are often violated by additional heterogeneities prevalent in scRNA-seq. Here we present SC-Pattern - an...

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Literature Corpus work: a0b9a09d-8cf0-5ddb-802e-ee5f8283ece0
DOI: 10.1101/046110

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