Article

Identification and quantification of alternative polyadenylation sites in single cell RNA-seq data using scPAISO

2025-08-25

Abstract excerpt

<h4>Abstracts</h4> Alternative polyadenylation (APA) is a critical posttranscriptional mechanism that generates transcriptomic diversity through the production of mRNA isoforms with distinct 3’ UTRs or coding sequences. Current APA analysis based on single-cell RNA sequencing (scRNA-seq) for establishing cell type-specific APA landscapes primarily rely on Read2 data, which lacks precise cleavage site (CS) informa...

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Literature Corpus work: 790ac7ee-5c03-5c91-af29-6d731294f2d0
DOI: 10.1101/2025.08.20.669565

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