Article

Cell-type-specific alternative polyadenylation (APA) genes reveal the function of dynamic APA in complex tissues

2020-07-31

Abstract excerpt

<h4>ABSTRACT</h4> Alternative polyadenylation (APA) causes shortening or lengthening of the 3’-untranslated region (3’-UTR) of genes across multiple cell types. Bioinformatic tools have been developed to identify genes that are affected by APA (APA genes) in single-cell RNA-Seq (scRNA-Seq) data. However, they suffer from low power, and they cannot identify APA genes specific to each cell type (cell-type-specific...

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Literature Corpus work: 199375b2-dc22-5205-b0b6-3283b13287b7
DOI: 10.1101/2020.07.30.229096

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