Article

Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance

2018-10-01

Abstract excerpt

<h4>SUMMARY</h4> The observation that humans can produce broadly neutralizing antibodies (bnAbs) against HIV-1 has generated enthusiasm about the potential for a bnAb vaccine against HIV-1. Conventional immunization strategies will likely be insufficient for the development of a bnAb HIV vaccine and vaccines to other difficult pathogens, due to the significant immunological hurdles posed, including B cell immunod...

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Literature Corpus work: abd7ff40-1d98-580e-a62a-9a7d90c9b994
DOI: 10.1101/432666

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