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A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions

2023-10-10

Abstract excerpt

<h4>ABSTRACT</h4> To eliminate vertical HIV transmission and achieve therapy-free viral suppression among children living with HIV, novel strategies beyond antiretroviral therapy (ART) are necessary. Our group previously identified a triple bNAb combination comprising of 3BNC117, PGDM1400 and PGT151 that mediates robust in vitro neutralization and non-neutralizing effector functions against a cross-clade panel o...

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Literature Corpus work
55af4daa-4c3a-54ee-97d6-6654ccd8fb60
DOI
10.1101/2023.10.09.561559
Open publication

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A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functionsDOI 10.1101/2023.10.09.561559
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