Article

Functional Convergence of Genetically Diverse B-Cell Receptors in Simian-HIV Infected Rhesus Macaques

2026-01-12

Abstract excerpt

<h4>SUMMARY</h4> Germline-targeting or lineage-design vaccine strategies are being used to induce HIV broadly neutralizing antibody (bnAb) responses. These strategies assume that genetically diverse individuals respond similarly to the same immunogen by mobilizing comparable germline precursors, although outcomes vary across bnAb epitopes. Here we explored this premise using a simian-HIV infection model in rhesus...

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Literature Corpus work: 12090dc9-22af-5468-b598-aac519281da6
DOI: 10.64898/2026.01.09.698730

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