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Article

The mucosal barrier and anti-viral immune responses can eliminate portions of the viral population during transmission and early viral growth.

PloS one - 1 Jan 2021

Moriarty Ryan V, Golfinos Athena E, Gellerup Dane D, Schweigert Hannah, Mathiaparanam Jaffna, Balgeman Alexis J, Weiler Andrea M, Friedrich Thomas C, Keele Brandon F, Davenport Miles P, Venturi Vanessa, O'Connor Shelby L

Abstract excerpt

Little is known about how specific individual viral lineages replicating systemically during acute Human Immunodeficiency Virus or Simian Immunodeficiency Virus (HIV/SIV) infection persist into chronic infection. In this study, we use molecularly barcoded SIV (SIVmac239M) to track distinct viral lineages for 12 weeks after intravenous (IV) or intrarectal (IR) challenge in macaques. Two Mafa-A1*063+ cynomolgus...

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Identifiers

PMID: 34855793
DOI: 10.1371/journal.pone.0260010
PMCID: PMC8639003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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