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Rapid vaccine induction of macaque HIV-1 V2 Apex broadly neutralizing antibodies with immunogenetic signatures that are potentially translatable to humans

2026-05-30

Abstract excerpt

<h4>ABSTRACT</h4> Due to the complex biology of HIV-1 broadly neutralizing antibodies (bnAbs), HIV-1 vaccines must target unmutated germline precursor antibodies with B cell receptors that have the appropriate specificity and genetic features to develop neutralization breadth. Previous work has shown that immunization or infection in macaques primes unmutated precursor antibodies that target the broadly neutraliz...

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Literature Corpus work
8f2d1c02-8416-54da-9034-65f5e758438a
DOI
10.64898/2026.05.27.728024
Open publication

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Rapid vaccine induction of macaque HIV-1 V2 Apex broadly neutralizing antibodies with immunogenetic signatures that are potentially translatable to humansDOI 10.64898/2026.05.27.728024
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