Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication.

doi:10.1128/JVI.00690-18

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Article

Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication.

Journal of virology - 15 Aug 2018

Martins Mauricio A, Tully Damien C, Pedreño-Lopez Núria, von Bredow Benjamin, Pauthner Matthias G, Shin Young C, Yuan Maoli, Lima Noemia S, Bean David J, Gonzalez-Nieto Lucas, Domingues Aline, Gutman Martin J, Maxwell Helen S, Magnani Diogo M, Ricciardi Michael J, Bailey Varian K, Altman John D, Burton Dennis R, Ejima Keisuke, Allison David B, Evans David T, Rakasz Eva G, Parks Christopher L, Bonaldo Myrna C, Capuano Saverio, Lifson Jeffrey D, Desrosiers Ronald C, Allen Todd M, Watkins David I

Abstract excerpt

Certain major histocompatibility complex class I (MHC-I) alleles are associated with spontaneous control of viral replication in human immunodeficiency virus (HIV)-infected people and simian immunodeficiency virus (SIV)-infected rhesus macaques (RMs). These cases of "elite" control of HIV/SIV replication are often immune-mediated, thereby providing a framework for studying anti-lentiviral immunity. In this study,...

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PMID: 29875239
DOI: 10.1128/JVI.00690-18
PMCID: PMC6069176

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Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication.PMID 29875239Read ↗

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