Article

A new experimental system to study meiotic recurrent non-allelic homologous recombination in budding yeast

2020-06-25

Abstract excerpt

<h4>ABSTRACT</h4> In humans, de novo recurrent copy number variations (CNVs) often arise during meiosis from non-allelic homologous recombination (NAHR) between low copy repeat elements (LCRs). These chromosomal rearrangements are responsible for a wide variety of genomic disorders involving duplication or deletion of dose-sensitive genes. The precise factors that steer meiotic cells toward this detrimental reco...

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Literature Corpus work: abb04fb3-f4f8-545c-980e-60ca8b974210
DOI: 10.1101/2020.06.25.164855

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