Article

Characterization of systemic genomic instability in budding yeast

2020-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Conventional models of genome evolution are centered around the principle that mutations form independently of each other and build up slowly over time. We characterized the occurrence of bursts of genome-wide loss-of-heterozygosity (LOH) in Saccharomyces cerevisiae , providing support for an additional non-independent and faster mode of mutation accumulation. We initially characterized a yeast...

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Literature Corpus work: 2f5a6c49-947b-56ba-8fbd-8eac2dfc4f28
DOI: 10.1101/2020.05.25.115535

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